How Does Qsymia Work?
Qsymia is a medication that combines two drugs, phentermine and extended-released topiramate, to reduce food intake and increase satiety. Phentermine is a central nervous system stimulant and appetite suppressant, while topiramate is an anticonvulsant used to treat epilepsy and prevent migraines.
The drug is believed to boost the activity of GABA, a neurotransmitter in the brain, which can help suppress appetite and create a feeling of fullness. Additionally, Qsymia may also alter the taste of certain foods. It is taken orally once a day as a long-term supplement to a reduced-calorie diet and increased physical exercise.
During 56-week clinical trials, patients who combined Qsymia 15/92 mg with diet and exercise lost an average of 14.5 kg (32 lb) and approximately 5 inches from their waist. In contrast, patients who received a placebo (an inactive pill with no medication) lost only 2.7 kg (6 lb) and 1.7 inches.